The outbreak of Coronavirus (Covid-19 or SARS-CoV-2) has implications for research and researchers at Barts Health and Queen Mary.
On this page we publish information to support our researchers, covering:
- Reopening clinical studies
- Celebrating 10,000 participants in Covid-19 research at Barts Health, 1 February 2021 [PDF 270KB]
- Statement on Barts Health research activity, 5 January 2021 [PDF 436KB]
- Get involved in our Covid-19 research
- New Covid-19 studies: The JRMO Covid-19 Review Committee
- Covid-19 vaccine research
- Travel policy for fieldwork
- Covid-19 data requests and project proposals: Barts Life Sciences' COVID-19 Data Group
- General clinical research guidance
- General non-clinical research guidance
- Guidance on continuing research at Queen Mary
- Guidance on remote monitoring of Barts Health clinical research
- Covid-19 studies open at Barts Health
- QMERC Covid-19 guidance
- Barts Health Knowledge and Library Services' Covid-19 Evidence updates, Clinical Decision Tool and related resources
- Queen Mary Doctoral College FAQ
Where clinical research studies were formally suspended at Barts Health and Queen Mary in 2020 and have yet to reopen, there are a number of factors to consider before that can happen. To help with that process the JRMO produced the following:
- Statement on the principles around reopening research studies [PDF 177KB]
- JRMO study restart assessment checklist [DOC 69KB]
The HRA has also published guidance on re-starting or making changes to existing studies that the JRMO will take into account.
All other studies, which had to be paused during the latest phase of the pandemic, can restart from 22 February 2021. However, Principal Investigators (PIs) should still consider if their study is urgent enough to warrant restart and if it is safe to restart. No formal restart process is required, but three principles will apply:
- The impact of the research on routine clinical workload - especially where there is significant strain;
- The need for experienced research staff who could make a life-saving contribution to patient care; and
- The implications for the safety of study participants.
In conjunction with these principles, PIs are reminded of their obligation to evaluate and minimise any risks of Covid-19 amongst both research staff and study participants. This should include consideration of travel to and from clinical sites, the need for infection prevention and control during including any necessary risk assessment for the research activities (in some cases poorly understood by researchers), aligning with clinical service priorities, and maintaining social distancing as per government guidelines.
The JRMO will prioritise study restart in accordance with the Prioritisation list for non-Covid research Sponsorship (February 2021) [DOC 15KB]
Please contact email@example.com to discuss where your study falls in the priority listing if that is unclear.
Barts Health is now running 'healthy volunteer' Covid-19 vaccine trials at its bespoke centre based at Bethnal Green Library, in the heart of East London. If you would like to take part in a vaccine study, send an email with your full name, and contact telephone number to firstname.lastname@example.org. You will be contacted by a member of the research team, who will explain more about the study.
NIHR ARC East Midlands has produced a useful document Public perceptions towards vaccine trial research within ethnic minority and vulnerable communities [PDF 343KB] which should be of assistance in tackling some commonly-held misconceptions that can act as a barrier to research inclusion.
The Barts Health website also has information, aimed primarily at patients, setting out how to get involved in the Trust's Covid-19 research. This is a very useful resource for research staff who need help with drafting information for patients or volunteers. The page covers such items as 'why do research into Covid-19', 'taking part in research', information about the Trust's PPIE Advisory Group, along with details of the Trust's major ongoing Covid-19 research projects. The JRMO's Engagement and Diffusion Team can help further with this.
The JRMO has published Guidance on the processes for both expedited study approval, and confirmation of capacity and capability, for all Barts Health and Queen Mary researchers in relation to the set-up of any new Covid-19-related research. Specifically, all new studies must be approved by the JRMO's Covid-19 Review Committee, which operates in accordance with Guiding Principles [PDF 178KB]
As of 8 January 2021, our Review Committee has met 39 times and reviewed a total of 380 research projects, including:
- 98 Clinical Effectiveness Unit (CEU) audit/service evaluations, and
- 83 QMERC studies
The NIHR has launched a central website where anyone can sign up to take part in a variety of expedited clinical trials relating to the development of a vaccine. More information about this work, including how to register as a volunteer, is available on the NIHR website.
Information about getting involved in other Covid-19 research is set out below.
If it is essential for you to do fieldwork for research continuation now, then you can do so provided you comply with the following. You must ensure you complete the risk assessment, and give specific consideration to local Covid-19 related policies of your institution, any institutions you will be working with and the governments of any countries outside the UK if the research is to be carried out overseas. Contact your line manager or supervisor for further information.
Risk assessments need to be signed off by your Head of School or Institute, and you must be aware that insurance cover will only remain valid if you can demonstrate to your Head of School or Institute that travel is necessary at this time and you can practice social distancing throughout the trip. Risk assessment templates for fieldwork are available on the HSD website.
The JRMO has published Guidance for site study teams and sponsors for remote monitoring and source data verification within Barts Health NHS Trust during the Covid-19 pandemic. This and additional JRMO guidance can be found on the guidance webpage.
Information about ongoing research into Covid-19 at Barts Health is on the Trust website. That page also includes links to videos encouraging patients to take part in both interventional and observational research, made in various languages found in East London.
Queen Mary Ethics of Research Committee (QMERC) Covid-19 guidance for researchers, 14 August 2020 [PDF 293KB]. There is also a QMERC webpage providing more information about its work.